The sweet allure of XNA

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Oligonucleotides with unnatural sugar backbones that can be replicated in vitro may open up new avenues for synthetic biology and beyond.

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Figure 1: Selection techniques for XNA-compatible polymerases.

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Correspondence to Larry Gold.

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Competing interests

F.S. and L.G. are employees and shareholders of SomaLogic.

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Steele, F., Gold, L. The sweet allure of XNA. Nat Biotechnol 30, 624–625 (2012) doi:10.1038/nbt.2298

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