ABSOLUTE cancer genomics

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Calculating absolute copy numbers in cancer genome sequences identifies disease-associated genes and provides insights into tumor evolution and heterogeneity.

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Figure 1: Biological insights obtained from sophisticated methods for copy number inference.

References

  1. 1

    Carter, S.L. et al. Nat. Biotechnol. 30, 413–421 (2012).

  2. 2

    Kallioniemi, A. et al. Science 258, 818–821 (1992).

  3. 3

    Bignell, G.R. et al. Nature 463, 893–898 (2010).

  4. 4

    Beroukhim, R. et al. Nature 463, 899–905 (2010).

  5. 5

    Popova, T. et al. Genome Biol. 10, R128 (2009).

  6. 6

    Van Loo, P. et al. Proc. Natl. Acad. Sci. USA 107, 16910–16915 (2010).

  7. 7

    Yau, C. et al. Genome Biol. 11, R92 (2010).

  8. 8

    Nik-Zainal, S. et al. Cell 149, 994–1007 (2012).

  9. 9

    Gerlinger, M. et al. N. Engl. J. Med. 366, 883–892 (2012)

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Correspondence to Peter Van Loo or Peter J Campbell.

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The authors declare no competing financial interests.

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Van Loo, P., Campbell, P. ABSOLUTE cancer genomics. Nat Biotechnol 30, 620–621 (2012) doi:10.1038/nbt.2293

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