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ABSOLUTE cancer genomics

Calculating absolute copy numbers in cancer genome sequences identifies disease-associated genes and provides insights into tumor evolution and heterogeneity.

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Figure 1: Biological insights obtained from sophisticated methods for copy number inference.

References

  1. Carter, S.L. et al. Nat. Biotechnol. 30, 413–421 (2012).

    Article  CAS  Google Scholar 

  2. Kallioniemi, A. et al. Science 258, 818–821 (1992).

    Article  CAS  Google Scholar 

  3. Bignell, G.R. et al. Nature 463, 893–898 (2010).

    Article  CAS  Google Scholar 

  4. Beroukhim, R. et al. Nature 463, 899–905 (2010).

    Article  CAS  Google Scholar 

  5. Popova, T. et al. Genome Biol. 10, R128 (2009).

    Article  Google Scholar 

  6. Van Loo, P. et al. Proc. Natl. Acad. Sci. USA 107, 16910–16915 (2010).

    Article  CAS  Google Scholar 

  7. Yau, C. et al. Genome Biol. 11, R92 (2010).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Nik-Zainal, S. et al. Cell 149, 994–1007 (2012).

    Article  CAS  Google Scholar 

  9. Gerlinger, M. et al. N. Engl. J. Med. 366, 883–892 (2012)

    Article  CAS  Google Scholar 

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Correspondence to Peter Van Loo or Peter J Campbell.

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Van Loo, P., Campbell, P. ABSOLUTE cancer genomics. Nat Biotechnol 30, 620–621 (2012). https://doi.org/10.1038/nbt.2293

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