Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Patents
  • Published:

Antibody specification beyond the target: claiming a later-generation therapeutic antibody by its target epitope

An Erratum to this article was published on 07 December 2012

This article has been updated

It may be possible to patent both antibodies to new targets and later-developed antibodies to known targets.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Change history

  • 07 December 2012

    In the version of this article initially published, in Table 1 “Patents claiming anti-TNFα antibodies”, patent US 7012135 should have been assigned to UCB Pharma and not UC Berkeley. The error has been corrected in the PDF and HTML versions of this article.

References

  1. Centocor Ortho Biotech, Inc. v. Abbott Laboratories, 636 F.3d 1341 (Fed. Cir. 2011).

  2. Id. p. 1348.

  3. Id. pp. 1349–1350.

  4. Id. p. 1353.

  5. US District Court for the Southern District of California; 10-CV-00608 BEN (GS), 18 October 2011 (claim construction order dkt. no. 60).

  6. Id. p. 6.

  7. Id. p. 14.

  8. Noelle v. Lederman, 355 F.3d 1343 (Fed. Cir. 2004); 2004 US App. LEXIS 774.

  9. European Patent Office Technical Board decision T0542/95, 1999, European Patent Office Board of Appeal decisions database no. T0542/95.

  10. Storz, U. IP issues of therapeutic antibodies. in SpringerBriefs in Biotech Patents 2012 (ed. Storz, U.) 1–12 (Springer, 2012).

    Google Scholar 

  11. See, for example, Abbott Biotechnology Ltd. v. Centocor Ortho Biotech Inc., 09cv40089, US District Court for the District of Massachusetts (Worcester); Abbott Labs. v. Bayer Healthcare, LLC, case no. 09-40002-FDS (D. Mass. 25 October 2010); and Bayer Healthcare, LLC v. Centocor Ortho Biotech, Inc., case no. 4:09-cv-11362-FDS (D. Mass. 23 December 2010).

Download references

Acknowledgements

The discussion above reflects solely the personal views and considerations of the authors and does not constitute either legal advice or the views of either Michalski · Hüttermann & Partner Patent Attorneys or Perkins Coie LLP. Thus, neither the authors nor Michalski · Hüttermann & Partner Patent Attorneys and Perkins Coie LLP can be bound either philosophically or as representatives of their various past, present and future clients to the comments and views expressed herein. Although every attempt has been made to ensure that the statements herein are accurate, errors or omissions may be present for which we disclaim any liability.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Colin G Sandercock or Ulrich Storz.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sandercock, C., Storz, U. Antibody specification beyond the target: claiming a later-generation therapeutic antibody by its target epitope. Nat Biotechnol 30, 615–618 (2012). https://doi.org/10.1038/nbt.2291

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.2291

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing