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DNA sequencing with nanopores

Major hurdles in the quest to sequence DNA with biological nanopores have now been overcome.

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Figure 1: Nanopores for DNA sequencing.

References

  1. Cherf et al. Nat. Biotechnol. 30, 344–348 (2012).

    Article  CAS  Google Scholar 

  2. Manrao et al. Nat. Biotechnol. 30, 349–353 (2012).

    Article  CAS  Google Scholar 

  3. Ansorge, W.J. New Biotechnol. 25, 195–203 (2009).

    Article  CAS  Google Scholar 

  4. Deamer, D.W. & Akeson, M. Trends Biotechnol. 18, 147–151 (2000).

    Article  CAS  Google Scholar 

  5. Kasianowicz, J.J., Brandin, E., Branton, D. & Deamer, D.W. Proc. Natl. Acad. Sci. 93, 13770–13773 (1996).

    Article  CAS  Google Scholar 

  6. Branton, D. et al. Nat. Biotechnol. 26, 1146–1153 (2008).

    Article  CAS  Google Scholar 

  7. Ashkenasy, N., Sanchez-Quesada, J., Bayley, H. & Ghadiri, M.R. Angew. Chem. Int. Ed. 44, 1401–1404 (2005).

    Article  CAS  Google Scholar 

  8. Stoddart, D., Heron, A.J., Mikhailova, E., Maglia, G. & Bayley, H. Proc. Natl. Acad. Sci. 106, 7702–7707 (2009).

    Article  CAS  Google Scholar 

  9. Vercoutere, W. et al. Nat. Biotechnol. 19, 248–252 (2001).

    Article  CAS  Google Scholar 

  10. Clarke, J. et al. Nat. Nanotechnol. 4, 265–270 (2009).

    Article  CAS  Google Scholar 

  11. Lieberman, K.R. et al. J. Am. Chem. Soc. 132, 17961–17972 (2010).

    Article  CAS  Google Scholar 

  12. Dekker, C. Nat. Nanotechnol. 2, 209–215 (2007).

    Article  CAS  Google Scholar 

  13. Schneider, G.F. et al. Nano Lett. 10, 3163–3167 (2010).

    Article  CAS  Google Scholar 

  14. Merchant, C.A. et al. Nano Lett. 10, 2915–2921 (2010).

    Article  CAS  Google Scholar 

  15. Garaj, S. et al. Nature 467, 190–193 (2010).

    Article  CAS  Google Scholar 

  16. Postma, H.W.C. Nano Lett. 10, 420–425 (2010).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Cees Dekker.

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Schneider, G., Dekker, C. DNA sequencing with nanopores. Nat Biotechnol 30, 326–328 (2012). https://doi.org/10.1038/nbt.2181

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