Selecting antigens for cancer vaccines

A cancer vaccine is streamlined by identifying a small set of potent immunogens in a tumor cDNA library.

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Figure 1: Screening to identify melanoma antigens in immune mice.

Katie Vicari

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Correspondence to Jedd D Wolchok.

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Competing interests

J.D.W. is a co-inventor on patents for xenogeneic DNA immunization and an alphavirus replicon particle vaccine for TRP2.

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Avogadri, F., Wolchok, J. Selecting antigens for cancer vaccines. Nat Biotechnol 30, 328–329 (2012). https://doi.org/10.1038/nbt.2174

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