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The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome

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Figure 1: Genomic, transcriptomic and protein information for the set of genes present in selected regions of chromosomes 13 and 17.


  1. Legrain, P. et al. Mol. Cell Proteomics 10, M111.009993 (2011).

  2. Hancock, W. et al. J. Proteome Res. 10, 210 (2011).

    Article  CAS  Google Scholar 

  3. Service, R.F. Science 321, 1758–1761 (2008).

    Article  CAS  Google Scholar 

  4. Lander, E.S. et al. Nature 409, 860–921 (2001)

    Article  CAS  Google Scholar 

  5. Farrah, T. et al. Mol. Cell. Proteomics 10, M110.006353 (2011).

  6. Menon, R. & Omenn, G.S. Methods Mol. Biol. 696, 319–326 (2011).

    Article  CAS  Google Scholar 

  7. Gnad, F. et al. Mol. Cell. Proteomics 9, 2642–2653 (2011).

    Article  Google Scholar 

  8. Walther, T.C. & Mann, M. J. Cell Biol. 190, 491–500 (2010).

    Article  CAS  Google Scholar 

  9. Uhlén, M. et al. Mol. Cell. Proteomics published online, doi: 10.1074/mcp.M111.013458 (31 October 2011).

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We thank R. Beavis for his critical comments and support for this work. Y.-K.P. thanks the Korean Human Proteome Organization HPP planning committee members for their contribution to the project in the early phase. Work involving chromosomes 13 and 17 in this paper was supported in part by the World Class University program funded by the Korean Ministry of Education, Science and Technology (to Y.-K.P. and W.S.H.), a grant from the Korean Ministry of Health and Welfare (to Y.-K.P.) and grants from the US National Cancer Institute (to M.S. and W.S.H.).

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Correspondence to Young-Ki Paik or William S. Hancock.

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Paik, YK., Jeong, SK., Omenn, G. et al. The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome. Nat Biotechnol 30, 221–223 (2012).

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