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Tracing the genesis of human embryonic stem cells

When human blastocysts are cultured in vitro to derive embryonic stem cells, they undergo profound molecular changes that alter their identity.

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Figure 1: Adaptation of human pluripotent cells during ESC derivation.

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Correspondence to Jacob H Hanna.

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Pribluda, A., Hanna, J. Tracing the genesis of human embryonic stem cells. Nat Biotechnol 30, 247–249 (2012). https://doi.org/10.1038/nbt.2139

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