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Harnessing cloud computing with Galaxy Cloud

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  1. Schatz, M.C., Langmead, B. & Salzberg, S.L. Nat. Biotechnol. 28, 691–693 (2010).

    CAS  Article  Google Scholar 

  2. Lieberman-Aiden, E. et al. Science 326, 289–293 (2009).

    CAS  Article  Google Scholar 

  3. Pepke, S., Wold, B. & Mortazavi, A. Nat. Methods 6, S22–S32 (2009).

    CAS  Article  Google Scholar 

  4. Wang, Z., Gerstein, M. & Snyder, M. Nat. Rev. Genet. 10, 57–63 (2009).

    CAS  Article  Google Scholar 

  5. Stein, L. Genome Biol. 11, 207 (2010).

    Article  Google Scholar 

  6. Langmead, B., Hansen, K.D. & Leek, J.T. Genome Biol. 11, R83 (2010).

    Article  Google Scholar 

  7. Langmead, B., Schatz, M.C., Lin, J., Pop, M. & Salzberg, S.L. Genome Biol. 10, R134 (2009).

    Article  Google Scholar 

  8. Schatz, M.C. Bioinformatics 25, 1363–1369 (2009).

    CAS  Article  Google Scholar 

  9. The 1000 Genomes Project Consortium. Nature 467, 1061–1073 (2010).

  10. Goecks, J., Nekrutenko, A. & Taylor, J. Genome Biol. 11, R86 (2010).

    Article  Google Scholar 

  11. Afgan, E. et al. in Guide to e-Science: Next Generation Scientific Research and Discovery (ed. Yang, K.) 35 (Springer, New York, 2011).

    Google Scholar 

  12. Afgan, E. et al. BMC Bioinformatics 11 Suppl 12, S4 (2010).

    Article  Google Scholar 

  13. DiMauro, S. Mitochondrion 4, 799–807 (2004).

    CAS  Article  Google Scholar 

  14. Taylor, R.W. & Turnbull, D.M. Nat. Rev. Genet. 6, 389–402 (2005).

    CAS  Article  Google Scholar 

  15. Goto, H., Dickins, B., Afgan, E., Paul, I.M., Taylor, J., Makova, K.D., Nekrutenko, A. Genome Biol. 12, R59 (2011).

    CAS  Article  Google Scholar 

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The authors are grateful to J. Beiler for coordinating sample collection, to clinical nurses from Penn State College of Medicine's Pediatric Clinical Research Office for collecting the samples and to volunteers for donating the samples. Efforts of the Galaxy Team (E.A., D.B., D. Blankenberg, N.C., J. Goecks, G. Von Kuster, R. Lazarus, K. Li & K. Vincent) were instrumental for making this work happen. This work was funded by US National Institutes of Health (NIH) grants HG005133 and HG005542 to J.T. and A.N., US National Science Foundation grant DBI 0543285 and NIH grant HG004909 to A.N. and J.T., and NIH grant GM07226405S2 to K.D.M. Additional funding is provided, in part, under a grant with the Pennsylvania Department of Health using Tobacco Settlement Funds. The Department specifically disclaims responsibility for any analyses, interpretations or conclusions.

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Correspondence to Kateryna D Makova, Anton Nekrutenko or James Taylor.

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Harnessing cloud-computing for biomedical research with Galaxy Cloud (PDF 229 kb)

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Afgan, E., Baker, D., Coraor, N. et al. Harnessing cloud computing with Galaxy Cloud. Nat Biotechnol 29, 972–974 (2011).

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