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Genome remodeling

Nature Biotechnology volume 29, pages 807–808 (2011)Cite this article

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Alteration of a stop codon across an entire bacterial genome opens the way to exploring the biotech potential of synthetic genetic codes.

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Figure 1: Simplified illustration of in vivo genome-wide codon replacement.

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Authors and Affiliations

  1. Yizhi Cai and Jef D. Boeke are in the Department of Molecular Biology and Genetics and the High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.,

    Yizhi Cai & Jef D Boeke

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  1. Yizhi Cai
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  2. Jef D Boeke
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Correspondence to Jef D Boeke.

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The authors declare no competing financial interests.

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Cai, Y., Boeke, J. Genome remodeling. Nat Biotechnol 29, 807–808 (2011). https://doi.org/10.1038/nbt.1964

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