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Knockout rats generated by embryo microinjection of TALENs

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Figure 1: Design and assay of TALENs that target rat IgM locus.

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Correspondence to Ignacio Anegon or Gregory J Cost.

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E.L., B.J.N., Y.S., A.I.V., X.M., L.Z., P.D.G, and G.J.C. are employees of Sangamo BioSciences. Sangamo BioSciences provided financial support for research in I.A.'s laboratory. Sangamo BioSciences has filed a patent application on the basis of these results.

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Tesson, L., Usal, C., Ménoret, S. et al. Knockout rats generated by embryo microinjection of TALENs. Nat Biotechnol 29, 695–696 (2011). https://doi.org/10.1038/nbt.1940

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