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SiRNA delivery with exosome nanoparticles

A natural system for ferrying RNA between cells is used to transport siRNA to the mouse brain.

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Figure 1: Advantages and drawbacks of siRNA delivery by exosomes, viruses, lipid nanoparticles or polymeric nanoparticles.

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Correspondence to Gunther Hartmann.

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van den Boorn, J., Schlee, M., Coch, C. et al. SiRNA delivery with exosome nanoparticles. Nat Biotechnol 29, 325–326 (2011). https://doi.org/10.1038/nbt.1830

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