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A mucosal gateway for vaccines

The use of a natural IgG transport system to deliver a mucosal vaccine is a step toward needle-free immunization.

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Figure 1: Likely mechanism by which intranasal delivery of a vaccine protects mice against intravaginal challenge with a lethal dose of HSV-2.

Marina Corral

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Correspondence to Jerry R McGhee.

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McGhee, J. A mucosal gateway for vaccines. Nat Biotechnol 29, 136–138 (2011). https://doi.org/10.1038/nbt.1766

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