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Brevetoxicosis

Red tides and marine mammal mortalities

Nature volume 435, pages755–756(2005)Cite this article

Unexpected brevetoxin vectors may account for deaths long after or remote from an algal bloom.

Abstract

Potent marine neurotoxins known as brevetoxins are produced by the ‘red tide’ dinoflagellate Karenia brevis. They kill large numbers of fish and cause illness in humans who ingest toxic filter-feeding shellfish or inhale toxic aerosols1. The toxins are also suspected of having been involved in events in which many manatees and dolphins died, but this has usually not been verified owing to limited confirmation of toxin exposure, unexplained intoxication mechanisms and complicating pathologies2,3,4. Here we show that fish and seagrass can accumulate high concentrations of brevetoxins and that these have acted as toxin vectors during recent deaths of dolphins and manatees, respectively. Our results challenge claims that the deleterious effects of a brevetoxin on fish (ichthyotoxicity) preclude its accumulation in live fish, and they reveal a new vector mechanism for brevetoxin spread through food webs that poses a threat to upper trophic levels.

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Figure 1: Brevetoxin concentrations in seagrass and fish during mass-mortality events.

References

  1. 1

    Steidinger, K. A. in Algal Toxins in Seafood and Drinking Water (ed. Falconer, I.) 1–28 (Academic, London, 1993).

    Google Scholar 

  2. 2

    Geraci, J. R. Clinical Investigation of the 1987–1988 Mass Mortality of Bottlenose Dolphins along the US Central and South Atlantic Coast. Report to the National Marine Fisheries Service and US Navy, Office of Naval Research and Marine Mammal Commission (Ontario Veterinary College, Guelph, Ontario, 1989).

    Google Scholar 

  3. 3

    O'Shea, T. J., Bonde, R. K., Buergelt, C. D. & Odell, D. K. Mar. Mamm. Sci. 7, 165–179 (1991).

    Article  Google Scholar 

  4. 4

    Van Dolah, F. M., Doucette, G. J., Gulland, F. M. D., Rowles, T. L. & Bossart, G. D. in Toxicology of Marine Mammals (eds Vos, J. G., Bossart, G. D., Fournier, M. & O'Shea, T. J.) 247–269 (Taylor & Francis, New York, 2003).

    Google Scholar 

  5. 5

    Bossart, G. D., Baden, D. G., Ewing, R. Y., Roberts, B. & Wright, S. D. Toxicol. Pathol. 26, 276–282 (1998).

    CAS  Article  PubMed  Google Scholar 

  6. 6

    Working Group on Marine Mammal Unusual Mortality Events The Bottlenose Dolphin (Tursiops truncatus): Unusual Mortality Event along the Panhandle of Florida March–April 2004 (National Marine Fisheries Service, 2004).

  7. 7

    Baden, D. G. & Mende, T. J. Toxicon 20, 457–461 (1982).

    CAS  Article  PubMed  Google Scholar 

  8. 8

    Pierce, R. H., Henry, M. S., Blum, P. & Payne, S. in Harmful Algal Blooms 2000 (eds Hallegraeff, G. M. et al.) 421–424 (Intergovernmental Oceanic Commission, Paris, 2001).

    Google Scholar 

  9. 9

    Ross, P. S. Hum. Ecol. Risk Ass. 6, 29–46 (2000).

    CAS  Article  Google Scholar 

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Author information

Affiliations

  1. Florida Fish and Wildlife Conservation Commission, Fish and Wildlife Research Institute, St Petersburg, 33701, Florida, USA

    Leanne J. Flewelling, Jay P. Abbott, Daniel G. Hammond, Elsa M. Haubold, Cynthia A. Heil, Thomas D. Pitchford, Sentiel A. Rommel, Paula S. Scott, Karen A. Steidinger, Earnest W. Truby & Jan H. Landsberg

  2. Center for Marine Science, University of North Carolina, Wilmington, 28409, North Carolina, USA

    Jerome P. Naar, Daniel G. Baden & Henry M. Jacocks

  3. Mote Marine Laboratory, Sarasota, 34236, Florida, USA

    Nélio B. Barros, Michael S. Henry & Richard H. Pierce

  4. Harbor Branch Oceanographic Institution, Fort Pierce, 34946, Florida, USA

    Gregory D. Bossart

  5. NOAA, NOS, Center for Coastal Environmental Health and Biomolecular Research, Charleston, 29412, South Carolina, USA

    Marie-Yasmine D. Bottein, Tod A. Leighfield & Frances M. Van Dolah

Authors
  1. Leanne J. Flewelling
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  2. Jerome P. Naar
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  3. Jay P. Abbott
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  4. Daniel G. Baden
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  5. Nélio B. Barros
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  6. Gregory D. Bossart
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  7. Marie-Yasmine D. Bottein
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  8. Daniel G. Hammond
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  9. Elsa M. Haubold
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  10. Cynthia A. Heil
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  11. Michael S. Henry
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  12. Henry M. Jacocks
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  13. Tod A. Leighfield
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  14. Richard H. Pierce
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  15. Thomas D. Pitchford
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  16. Sentiel A. Rommel
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  17. Paula S. Scott
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  18. Karen A. Steidinger
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  19. Earnest W. Truby
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  20. Frances M. Van Dolah
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  21. Jan H. Landsberg
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Corresponding author

Correspondence to Jerome P. Naar.

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The authors declare no competing financial interests.

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Cite this article

Flewelling, L., Naar, J., Abbott, J. et al. Red tides and marine mammal mortalities. Nature 435, 755–756 (2005). https://doi.org/10.1038/nature435755a

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