Extended Data Figure 8 : Predicted chromatin state for recurrently mutated elements.

From: De novo mutations in regulatory elements in neurodevelopmental disorders

Extended Data Figure 8

chromHMM state of the n = 31 recurrently mutated elements shows enrichment for enhancers and transcribed elements. Elements that overlapped a high confidence DHS but were predicted as quiescent by chromHMM are classed as Overlaps DHS. P values derived from Poisson distribution with parameter lambda defined by the simulated data.