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Author information

Author notes

    • Carla Vicinanza
    •  & Iolanda Aquila

    These authors contributed equally to this work.

    • Bernardo Nadal-Ginard
    •  & Daniele Torella

    These authors jointly supervised this work.

Affiliations

  1. Molecular and Cellular Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro 88100, Italy

    • Carla Vicinanza
    • , Iolanda Aquila
    • , Eleonora Cianflone
    • , Mariangela Scalise
    • , Fabiola Marino
    • , Teresa Mancuso
    • , Enrico Iaccino
    • , Pina Marotta
    • , Ciro Indolfi
    • , Bernardo Nadal-Ginard
    •  & Daniele Torella
  2. IRCCS - Istituto di Ricerche Farmacologiche “Mario Negri”, Milan 20156, Italy

    • Francesca Fumagalli
    •  & Roberto Latini
  3. CIS for Genomics and Molecular Pathology, Magna Graecia University, Catanzaro 88100, Italy

    • Emilia Dora Giovannone
    •  & Valter Agosti
  4. Bioinformatics, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro 88100, Italy

    • Francesca Cristiano
    •  & Pierangelo Veltri
  5. Department of Biochemistry, Biophysics and General Pathology, University of Campania “L. Vanvitelli”, Naples 80121, Italy

    • Annalaura Torella
  6. Department of Experimental Medicine, Section of Pharmacology, University of Campania “L. Vanvitelli”, Naples 80121, Italy

    • Konrad Urbanek
  7. Department of Experimental Medicine, “La Sapienza” University, Rome 00161, Italy.

    • Andrea M. Isidori
  8. Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany

    • Dieter Saur
  9. Chair of Translational Cancer Research and Department of Medicine II, School of Medicine, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany

    • Dieter Saur

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Contributions

D.T. and B.N.-G. designed the research studies, analysed data and wrote the manuscript. C.V., I.A., E.C., M.S., F.M., T.M., F.F., E.D.G., E.I., P.M., V.A. and K.U. conducted the experiments, acquired and analysed data. F.C., A.T. and P.V. conducted RNA-sequencing experiments and analysed bioinformatic data. R.L., A.M.I., D.S. and C.I. contributed reagents. All authors approved the manuscript.

Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Bernardo Nadal-Ginard or Daniele Torella.

Extended data

Supplementary information

PDF files

  1. 1.

    Supplementary Information

    This file contains Supplementary Materials and Methods, Supplementary References, Supplementary Figure 1 and Supplementary Table 1.

Videos

  1. 1.

    High magnification of a beating wild type CSC-derived Cardiosphere

    This video shows a beating wild type CSC-derived Cardiosphere in high magnification.

About this article

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DOI

https://doi.org/10.1038/nature25771

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