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Contesting the evidence for non-adaptive plasticity

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Figure 1: Negative correlations between ancestral plasticity and divergence in gene expression, and between the magnitude of plasticity in the source population and the evolved mean change in plasticity.
Figure 2: Schematic representation of the negative correlation between the changes in gene expression observed in the predator-free environment and the ancestral plasticity when all values are randomly sampled from a normal distribution.


  1. Ghalambor, C. K. et al. Non-adaptive plasticity potentiates rapid adaptive evolution of gene expression in nature. Nature 525, 372–375 (2015)

    Article  ADS  CAS  Google Scholar 

  2. Galton, F. Regression towards mediocrity in hereditary stature. J. Anthropol. Inst. G. B. Irel. 15, 246–263 (1886)

    Google Scholar 

  3. Barnett, A. G., van der Pols, J. C. & Dobson, A. J. Regression to the mean: what it is and how to deal with it. Int. J. Epidemiol. 34, 215–220 (2005)

    Article  Google Scholar 

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F.M. performed simulations and analysed the data. F.M., A.M.J. and C.S. conceived the study and wrote the manuscript.

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Correspondence to Christian Schlötterer.

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The authors declare no competing financial interests.

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This file contains Supplementary Text, Supplementary Figures 1-5 and a Supplementary Reference. (PDF 375 kb)

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Mallard, F., Jakšić, A. & Schlötterer, C. Contesting the evidence for non-adaptive plasticity. Nature 555, E21–E22 (2018).

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