Extended Data Figure 4: Overview of type-II ABC exporters and PglK. | Nature

Extended Data Figure 4: Overview of type-II ABC exporters and PglK.

From: Architecture of a channel-forming O-antigen polysaccharide ABC transporter

Extended Data Figure 4

a, The structures of the transmembrane domains of A. aeolicus Wzm, Homo sapiens ABCG5 and H. sapiens ABCA1 are shown as cylindrical cartoons. One subunit of the dimers is coloured in rainbow colours from blue to red, N terminus to C terminus. b, Structure of PglK, an ABC transporter translocating UND-PP-linked oligosaccharides across the plasma membrane. PglK probably recognizes the polyprenyl moiety of the substrate via a conserved periplasmic helix (shown in magenta), which is missing in Wzm.

Back to article page