Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Gene therapy

Transgenic stem cells replace skin

The treatment of a patient affected by an incurable genetic skin disease demonstrates the efficacy, feasibility and safety of replacing almost the whole skin using genetically corrected stem cells. See Letter p.327

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Gene therapy to treat a skin disease.


  1. See all news & views


  1. Trounson, A. & McDonald, C. Cell Stem Cell 17, 11–22 (2015).

    Article  CAS  Google Scholar 

  2. Hirsch, T. et al. Nature 551, 327–332 (2017).

    Article  ADS  CAS  Google Scholar 

  3. Blanpain, C. & Fuchs, E. Nature Rev. Mol. Cell Biol. 10, 207–217 (2009).

    Article  CAS  Google Scholar 

  4. DeStefano, G. M. & Christiano, A. Cold Spring Harb. Perspect. Med. 4, a015172 (2014).

    Article  Google Scholar 

  5. Mavilio, F. et al. Nature Med. 12, 1397–1402 (2006).

    Article  CAS  Google Scholar 

  6. Blanpain, C. & Simons, B. D. Nature Rev. Mol. Cell Biol. 14, 489–502 (2013).

    Article  CAS  Google Scholar 

  7. Barrandon, Y. & Green, H. Proc. Natl Acad. Sci. USA 84, 2302–2306 (1987).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Cédric Blanpain.

Related audio

Related links

Related links

Related links in Nature Research

Gene therapy: Repair and replace

Stem cells: Skin regeneration and repair

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Aragona, M., Blanpain, C. Transgenic stem cells replace skin. Nature 551, 306–307 (2017).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research