Extended Data Table 1: FT671 and FT827 specificity

From: Molecular basis of USP7 inhibition by selective small-molecule inhibitors

Table 1
  1. Tabulated specificity data of FT671 and FT827 at 50 μM against a panel of named DUBs of different families, graphically depicted in Fig. 1b. (1) Addition of ubiquitin at Kd; (2) addition of ubiquitin at Bmax; (3) in the presence of proteasome-vinyl sulfone at Kd; (4) USP10 and USP47 were tested individually at 25 μM FT671. N.D., not determined.