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Epitranscriptomics

Shrinking maps of RNA modifications

Nature volume 551, pages 174–176 (2017)Cite this article

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The presence of N1 methyl groups on adenine bases was thought to be widespread in messenger RNAs. It now seems that these modifications are much less prevalent, and occur on mRNAs that structurally mimic transfer RNA. See Letter p.251

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Figure 1: Mimicry of non-coding RNA structures by messenger RNA directs nucleotide modification.

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Authors and Affiliations

  1. Department of Pharmacology, Weill Cornell Medicine, Cornell University, New York, 10065, New York, USA

    Anya V. Grozhik & Samie R. Jaffrey

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  1. Anya V. Grozhik
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  2. Samie R. Jaffrey
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Correspondence to Samie R. Jaffrey.

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Molecular biology: RNA modification does a regulatory two-step

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Grozhik, A., Jaffrey, S. Shrinking maps of RNA modifications. Nature 551, 174–176 (2017). https://doi.org/10.1038/nature24156

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