Rett syndrome is a brain disorder caused by disrupted forms of the protein MECP2, but how MECP2 loss affects the brain is unknown. A mouse study now implicates key domains of the protein and offers therapeutic insights. See Letter p.398
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Tapping-lips aggravated interictal bilateral discharges in EEG in the patients with Rett syndrome: a case report
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West, A. Domains to the rescue for Rett syndrome. Nature 550, 343–344 (2017). https://doi.org/10.1038/nature24151
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DOI: https://doi.org/10.1038/nature24151