The cellular origins of a precancerous condition called Barrett's oesophagus have been unclear. Tracking and analysis of epithelial cells at the affected site could shed light on the problem. See Letter p.529
This is a preview of subscription content, access via your institution
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 per month
cancel any time
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Jiang, M. et al. Nature 550, 529–533 (2017).
Giroux, V. & Rustgi, A. K. Nature Rev. Cancer 17, 594–604 (2017).
McDonald, S. A., Lavery, D., Wright, N. A. & Jansen, M. Nature Rev. Gastroenterol. Hepatol. 12, 50–60 (2015).
Spechler, S. J. & Souza, R. F. N. Engl. J. Med. 371, 836–845 (2014).
Glickman, J. N., Chen, Y. Y., Wang, H. H., Antonioli, D. A. & Odze, R. D. Am. J. Surg. Pathol. 25, 569–578 (2001).
Cabibi, D. et al. Med. Sci. Monit. 15, CR203–CR210 (2009).
Coleman, H. G., Xie, S.-H. & Lagergren, J. Gastroenterology http://dx.doi.org/10.1053/j.gastro.2017.07.046 (2017).
Phillips, R. W., Frierson, H. F. & Moskaluk, C. A. Am. J. Surg. Pathol. 27, 1442–1447 (2003).
Blokzijl, F. et al. Nature 538, 260–264 (2016).
Ross-Innes, C. S. et al. Nature Genet. 47, 1038–1046 (2015).
Hamilton, S. R. & Yardley, J. H. Gastroenterology 72, 669–675 (1977).
Related links in Nature Research
Cancer genomics: Spot the difference
Rights and permissions
About this article
Cite this article
Zhuang, L., Fitzgerald, R. Origins in the oesophagus. Nature 550, 463–464 (2017). https://doi.org/10.1038/nature24150