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Chromosome biology

How to build a cohesive genome in 3D

Nature volume 551, pages 38–40 (2017)Cite this article

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Removing the protein complex cohesin from chromosomes destroys one layer of the genome's 3D structure but leaves another intact. Genome structure is therefore built by independent processes that work together. See Letter p.51

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Figure 1: Unpacking chromosome organization.

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Authors and Affiliations

  1. Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, 37996, Tennessee, USA

    Rachel Patton McCord

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  1. Rachel Patton McCord
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Correspondence to Rachel Patton McCord.

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McCord, R. How to build a cohesive genome in 3D. Nature 551, 38–40 (2017). https://doi.org/10.1038/nature24145

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