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Evolution

Zapping viral RNAs

The discovery that the host defence protein ZAP specifically targets viral RNAs that are rich in a particular pair of adjacent bases — cytosine followed by guanine — sheds light on the evolution of viral RNA genomes. See Letter p.124

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Figure 1: ZAP protein selectively binds and blocks specific RNA viruses.

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Correspondence to Stephen P. Goff.

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Goff, S. Zapping viral RNAs. Nature 550, 46–47 (2017). https://doi.org/10.1038/nature24140

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