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Vitamin C regulates stem cells and cancer

It emerges that high levels of vitamin C in blood-forming stem cells influence the number and function of the cells and affect the development of leukaemia, through binding to a tumour-suppressor protein, Tet2. See Article p.476

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Figure 1: The effects of vitamin C on stem-cell biology and leukaemia.


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Correspondence to Benjamin L. Ebert.

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Miller, P., Ebert, B. Vitamin C regulates stem cells and cancer. Nature 549, 462–464 (2017).

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