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Division hierarchy leads to cell heterogeneity


Cellular diversity can hamper cancer treatment. Analysis of tumour cell-division patterns now reveals how such heterogeneity can arise by a hierarchical pattern of stem-cell divisions yielding a mosaic of different cells. See Article p.227

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Figure 1: Tracking cellular heterogeneity in cancer.


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Correspondence to Joan Seoane.

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Seoane, J. Division hierarchy leads to cell heterogeneity. Nature 549, 164–166 (2017).

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