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Global health

Probiotic prevents infections in newborns

A major cause of death and disease in babies is the failure of their developing immune systems to block life-threatening infections. A clinical trial reports that the use of a probiotic can help to prevent such infections. See Article p.407

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Figure 1: A clinical trial to prevent sepsis.


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  2. Goenka, A. & Kollmann, T. R. J. Infect. 71 (Suppl. 1), S112–S120 (2015).

    Article  Google Scholar 

  3. Shane, A. L., Sánchez, P. J. & Stoll, B. J. Lancet (2017).

    Article  Google Scholar 

  4. Panigrahi, P. et al. Nature 548, 407–412 (2017).

    ADS  CAS  Article  Google Scholar 

  5. Gibson, G. R. & Roberfroid, M. B. J. Nutr. 125, 1401–1412 (1995).

    CAS  Article  Google Scholar 

  6. Dermyshi, E. et al. Neonatology 112, 9–23 (2017).

    CAS  Article  Google Scholar 

  7. Rao, S. C., Athalye-Jape, G. K., Deshpande, G. C., Simmer, K. N. & Patole, S. K. Pediatrics 137, e20153684 (2016).

    Article  Google Scholar 

  8. GBD 2015 Mortality and Causes of Death Collaborators. Lancet 388, 1459–1544 (2016).

  9. Ballard, O. & Morrow, A. L. Pediatr. Clin. N. Am. 60, 49–74 (2013).

    Article  Google Scholar 

  10. Panigrahi, P. et al. J. Pediatr. Gastroenterol. Nutr. 47, 45–53 (2008).

    Article  Google Scholar 


  12. The Young Infants Clinical Signs Study Group. Lancet 371, 135–142 (2008).

  13. Seale, A. C. et al. Lancet Infect. Dis. 14, 731–741 (2014).

    Article  Google Scholar 

  14. Budden, K. F. et al. Nature Rev. Microbiol. 15, 55–63 (2017).

    CAS  Article  Google Scholar 

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Correspondence to Daniel J. Tancredi.

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Competing interests

The author has received research support and consultation fees from the International Scientific Association for Probiotics and Prebiotics, a non-profit scientific society.

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Tancredi, D. Probiotic prevents infections in newborns. Nature 548, 404–405 (2017).

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