Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Global health

Probiotic prevents infections in newborns

A major cause of death and disease in babies is the failure of their developing immune systems to block life-threatening infections. A clinical trial reports that the use of a probiotic can help to prevent such infections. See Article p.407

Your institute does not have access to this article

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: A clinical trial to prevent sepsis.

Notes

  1. See all news & views

References

  1. http://vizhub.healthdata.org/gbd-compare

  2. Goenka, A. & Kollmann, T. R. J. Infect. 71 (Suppl. 1), S112–S120 (2015).

    Article  Google Scholar 

  3. Shane, A. L., Sánchez, P. J. & Stoll, B. J. Lancet https://doi.org/10.1016/S0140-6736(17)31002-4 (2017).

    Article  Google Scholar 

  4. Panigrahi, P. et al. Nature 548, 407–412 (2017).

    ADS  CAS  Article  Google Scholar 

  5. Gibson, G. R. & Roberfroid, M. B. J. Nutr. 125, 1401–1412 (1995).

    CAS  Article  Google Scholar 

  6. Dermyshi, E. et al. Neonatology 112, 9–23 (2017).

    CAS  Article  Google Scholar 

  7. Rao, S. C., Athalye-Jape, G. K., Deshpande, G. C., Simmer, K. N. & Patole, S. K. Pediatrics 137, e20153684 (2016).

    Article  Google Scholar 

  8. GBD 2015 Mortality and Causes of Death Collaborators. Lancet 388, 1459–1544 (2016).

  9. Ballard, O. & Morrow, A. L. Pediatr. Clin. N. Am. 60, 49–74 (2013).

    Article  Google Scholar 

  10. Panigrahi, P. et al. J. Pediatr. Gastroenterol. Nutr. 47, 45–53 (2008).

    Article  Google Scholar 

  11. http://apps.who.int/iris/bitstream/10665/254502/1/WHO-MCA-17.01-eng.pdf

  12. The Young Infants Clinical Signs Study Group. Lancet 371, 135–142 (2008).

  13. Seale, A. C. et al. Lancet Infect. Dis. 14, 731–741 (2014).

    Article  Google Scholar 

  14. Budden, K. F. et al. Nature Rev. Microbiol. 15, 55–63 (2017).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel J. Tancredi.

Ethics declarations

Competing interests

The author has received research support and consultation fees from the International Scientific Association for Probiotics and Prebiotics, a non-profit scientific society.

Related links

Related links

Related links in Nature Research

In Retrospect: Global health estimated over two decades

Population health: Immaturity in the gut microbial community

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Tancredi, D. Probiotic prevents infections in newborns. Nature 548, 404–405 (2017). https://doi.org/10.1038/nature23540

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature23540

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing