Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cancer genomics

Human metastases under scrutiny


Sequences of the DNA and RNA of 500 human cancers that have spread from their primary site in the body take us a step closer to the convergence of basic science and patient benefit. See Article p.297

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout


  1. See all news & views


  1. Robinson, D. R. et al. Nature 548, 297–303 (2017).

    Article  ADS  CAS  Google Scholar 

  2. Robinson, D. et al. Cell 161, 1215–1228 (2015).

    Article  CAS  Google Scholar 

  3. Roychowdhury, S. Sci. Transl. Med. 3, 111ra121 (2011).

    Article  Google Scholar 

  4. Yoshihara, K. et al. Nature Commun. 4, 2612 (2013).

    Google Scholar 

  5. Nowell, P. C. Science 194, 23–28 (1976).

    Article  ADS  CAS  Google Scholar 

  6. Yachida, S. et al. Nature 467, 1114–1117 (2010).

    Google Scholar 

  7. Gerlinger, M. et al. N. Engl. J. Med. 366, 883–892 (2012).

    Article  CAS  Google Scholar 

  8. Gundem, G. et al. Nature 520, 353–357 (2015).

    Article  CAS  Google Scholar 

  9. Hong, M. K. H. et al. Nature Commun. 6, 6605 (2015).

    Article  CAS  Google Scholar 

  10. Nik-Zainal, S. et al. Cell 149, 994–1007 (2012).

    Article  CAS  Google Scholar 

  11. Diaz., L. A. Jr et al. Nature 486, 537–540 (2012).

    Article  ADS  CAS  Google Scholar 

  12. Bova, G. S. et al. Cold Spring Harb. Mol. Case Stud. 2, a000752 (2016).

    Article  Google Scholar 

  13. Abbosh, C. et al. Nature 545, 446–451 (2017).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to G. Steven Bova.

Related links

Related links

Related links in Nature Research

Cancer: Genomic evolution of metastasis

Genomics: Comparisons across cancers

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bova, G. Human metastases under scrutiny. Nature 548, 287–288 (2017).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer