Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Cancer genomics

Human metastases under scrutiny


Sequences of the DNA and RNA of 500 human cancers that have spread from their primary site in the body take us a step closer to the convergence of basic science and patient benefit. See Article p.297

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    See all news & views


  1. 1

    Robinson, D. R. et al. Nature 548, 297–303 (2017).

    ADS  CAS  Article  Google Scholar 

  2. 2

    Robinson, D. et al. Cell 161, 1215–1228 (2015).

    CAS  Article  Google Scholar 

  3. 3

    Roychowdhury, S. Sci. Transl. Med. 3, 111ra121 (2011).

    Article  Google Scholar 

  4. 4

    Yoshihara, K. et al. Nature Commun. 4, 2612 (2013).

    Google Scholar 

  5. 5

    Nowell, P. C. Science 194, 23–28 (1976).

    ADS  CAS  Article  Google Scholar 

  6. 6

    Yachida, S. et al. Nature 467, 1114–1117 (2010).

    Google Scholar 

  7. 7

    Gerlinger, M. et al. N. Engl. J. Med. 366, 883–892 (2012).

    CAS  Article  Google Scholar 

  8. 8

    Gundem, G. et al. Nature 520, 353–357 (2015).

    CAS  Article  Google Scholar 

  9. 9

    Hong, M. K. H. et al. Nature Commun. 6, 6605 (2015).

    CAS  Article  Google Scholar 

  10. 10

    Nik-Zainal, S. et al. Cell 149, 994–1007 (2012).

    CAS  Article  Google Scholar 

  11. 11

    Diaz., L. A. Jr et al. Nature 486, 537–540 (2012).

    ADS  CAS  Article  Google Scholar 

  12. 12

    Bova, G. S. et al. Cold Spring Harb. Mol. Case Stud. 2, a000752 (2016).

    Article  Google Scholar 

  13. 13

    Abbosh, C. et al. Nature 545, 446–451 (2017).

    ADS  CAS  Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to G. Steven Bova.

Related links

Related links

Related links in Nature Research

Cancer: Genomic evolution of metastasis

Genomics: Comparisons across cancers

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Bova, G. Human metastases under scrutiny. Nature 548, 287–288 (2017).

Download citation


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing