The results of in vitro and in vivo screens to identify genes that are essential for the survival of a type of brain cancer show almost no overlap, underlining the need for caution when interpreting in vitro studies. See Letter p355.
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Northcott, P. Keeping it real to kill glioblastoma. Nature 547, 291–292 (2017). https://doi.org/10.1038/nature23095
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DOI: https://doi.org/10.1038/nature23095