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Molecular biology

A liquid reservoir for silent chromatin

Nature volume 547, pages 168170 (13 July 2017) | Download Citation

The protein HP1 mediates compaction of DNA into a repressive structure called heterochromatin. Analysis reveals that HP1 has liquid-like properties, offering a fresh perspective on genome organization. See Letters p.236 & p.241

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References

  1. 1.

    et al. Science 324, 1729–1732 (2009).

  2. 2.

    , & Annu. Rev. Cell Dev. Biol. 30, 39–58 (2014).

  3. 3.

    , , & Nature Rev. Mol. Cell Biol. 18, 285–298 (2017).

  4. 4.

    et al. Nature 547, 241–245 (2017).

  5. 5.

    et al. Nature 547, 236–240 (2017).

  6. 6.

    & Nature Rev. Mol. Cell Biol. 10, 243–254 (2009).

  7. 7.

    et al. Cell 165, 1686–1697 (2016).

  8. 8.

    & Cold Spring Harb. Perspect. Biol. 7, a019323 (2015).

  9. 9.

    et al. Cell 163, 123–133 (2015).

  10. 10.

    et al. Cell 166, 1572–1584 (2016).

  11. 11.

    et al. Mol. Cell 57, 936–947 (2015).

  12. 12.

    & Genetics 19, 189–208 (1934).

  13. 13.

    , , & Cell 76, 157–169 (1994).

  14. 14.

    & Cold Spring Harb. Perspect. Biol. 6, a019471 (2014).

  15. 15.

    , , , & Cell 169, 13–23 (2017).

  16. 16.

    , , & Curr. Opin. Genet. Dev. 37, 36–45 (2016).

Download references

Author information

Affiliations

  1. Adam Klosin and Anthony A. Hyman are at the Max Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.

    • Adam Klosin
    •  & Anthony A. Hyman

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Correspondence to Adam Klosin or Anthony A. Hyman.

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DOI

https://doi.org/10.1038/nature23089

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