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Molecular biology

A liquid reservoir for silent chromatin

The protein HP1 mediates compaction of DNA into a repressive structure called heterochromatin. Analysis reveals that HP1 has liquid-like properties, offering a fresh perspective on genome organization. See Letters p.236 & p.241

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Figure 1: Chromatin compaction in liquid droplets.

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Correspondence to Adam Klosin or Anthony A. Hyman.

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Klosin, A., Hyman, A. A liquid reservoir for silent chromatin. Nature 547, 168–169 (2017). https://doi.org/10.1038/nature23089

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