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Bacterial pathogens

A spoonful of sugar could be the medicine

Pili are filamentous bacterial structures that promote adhesion to host cells. It emerges that a small molecule that inhibits this adhesion can prevent colonization of the mouse gut by a pathogenic bacterium. See Letter p.528

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Figure 1: A small molecule clears pathogens from the gut.


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Correspondence to Eric G. Pamer.

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Jung, HJ., Pamer, E. A spoonful of sugar could be the medicine. Nature 546, 479–480 (2017).

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