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Cell cycle

Division enzyme regulates metabolism

Cell division requires the action of key regulator proteins called cyclins and CDKs. It emerges that a cyclin–CDK complex can regulate cell metabolism, and targeting this metabolic regulation causes tumour regression in mice. See Letter p.426

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Figure 1: Cell-cycle enzymes can affect cellular metabolism.

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Correspondence to Heather R. Christofk.

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Krall, A., Christofk, H. Division enzyme regulates metabolism. Nature 546, 357–358 (2017). https://doi.org/10.1038/nature22504

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