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Molecular biology

Local metabolites linked to memory

Production of the metabolite acetyl-CoA near specific regions of DNA modulates gene expression in mouse neurons during cellular differentiation and memory formation. See Article p.381

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Figure 1: From metabolic signalling to gene regulation through chromatin.

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Correspondence to Li-Huei Tsai.

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Watson, L., Tsai, LH. Local metabolites linked to memory. Nature 546, 361–362 (2017). https://doi.org/10.1038/nature22498

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