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Ageing

Tools to eliminate senescent cells

Ageing and many diseases are partly driven by the accumulation of damaged cells that no longer divide. It emerges that these senescent cells can be eradicated in mice using a drug that interferes with the activity of the protein FOXO4.

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Figure 1: Targeting a damaged cell population.

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Correspondence to Manuel Serrano.

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Serrano, M. Tools to eliminate senescent cells. Nature 545, 294–295 (2017). https://doi.org/10.1038/nature22493

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