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Molecular biology

The long and short of a DNA-damage response

Ultraviolet light can damage DNA, triggering a general shutdown of gene transcription — yet some genes are activated by UV light. An investigation of this counter-intuitive behaviour reveals a surprising gene-regulation mechanism.

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Figure 1: Ultraviolet irradiation alters RNA processing.


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Correspondence to Antonio Conconi or Brendan Bell.

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Conconi, A., Bell, B. The long and short of a DNA-damage response. Nature 545, 165–166 (2017).

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