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Molecular genetics

Chaperone protein gets personal

Two studies of the molecular chaperone protein HSP90 reveal how complex traits can be shaped by genetic and environmental context. This work highlights the challenges of personalized medicine.

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Figure 1: Heat-shock protein 90 (HSP90) alters the effects of genetic differences.

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Correspondence to Mark L. Siegal.

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Siegal, M. Chaperone protein gets personal. Nature 545, 36–37 (2017). https://doi.org/10.1038/nature22487

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