Extended Data Figure 4 : Carriers of pLoF alleles in CYP2F1 have increased IL-8 concentrations.

From: Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

Extended Data Figure 4

Participants who had pLoF mutations in the CYP2F1 gene had higher concentrations of IL-8, whereas heterozygotes had a more modest effect when compared to the rest of the cohort of non-carriers. IL-8 concentration is natural log transformed. Bars represent 1.5× interquartile range beyond the 25th and 75th percentiles.