Extended Data Figure 3 : QQ-plot of recessive model pLoF association analysis across phenotypes.

From: Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

Extended Data Figure 3

Analyses to determine whether homozygous pLoF carrier status was associated with traits was performed where there were at least two homozygous pLoF carriers phenotyped per trait. The observed versus the expected results from 15,263 associations are displayed here demonstrating an excess of associations beyond a Bonferroni threshold.