Extended Data Figure 6 : Nondiabetic homozygous pLoF carriers for A3GALT2 have diminished insulin C-peptide concentrations.

From: Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

Extended Data Figure 6

Among nondiabetics, those who were homozygous pLoF for A3GALT2 had substantially lower fasting insulin C-peptide concentrations. This observation was not evident in nondiabetic heterozygous pLoF A3GALT2 participants. Insulin C-peptide is natural log transformed. Bars represent 1.5× interquartile range beyond the 25th and 75th percentiles.