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Neurodegenerative disease

Two–for–one on potential therapies

Molecules that inhibit the synthesis of the ataxin 2 protein can ameliorate the effects of two neurodegenerative diseases in mouse models, raising hopes for the success of this approach in clinical trials. See Letters p.362 & p.367

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Figure 1: A shared strategy for treating two neurodegenerative diseases.


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Correspondence to Ke Zhang or Jeffrey D. Rothstein.

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Zhang, K., Rothstein, J. Two–for–one on potential therapies. Nature 544, 302–303 (2017).

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