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Structural biology

Receptors grease the metabolic wheels

Structural insights into adiponectin receptors provide evidence that these proteins have an inherent enzymatic activity, which gives them the ability to propagate signalling by their ligand, the hormone adiponectin. See Letter p.120

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Figure 1: Adiponectin receptor activity crystallized.


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Correspondence to Philipp E. Scherer.

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Holland, W., Scherer, P. Receptors grease the metabolic wheels. Nature 544, 42–43 (2017).

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