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Aggregates are aberrant, non-functional forms of protein that often build up in cells in response to stress. Organelles called mitochondria have now been found to be active players in the clearance of these protein aggregates. See Letter p.443

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Figure 1: Disposal of aggregating proteins by mitochondria.

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Correspondence to Agnieszka Chacinska.

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Chacinska, A. Sort and destroy. Nature 543, 324–325 (2017). https://doi.org/10.1038/nature21892

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