Ageing is associated with an increased risk of cardiovascular disease caused by the rupture of inflamed cholesterol plaques in arteries. It emerges that this might be partly due to genetic mutations that cause cancerous changes in white blood cells.
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PS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation
Nutrition & Metabolism Open Access 01 June 2021
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References
Fuster, J. J. et al. Science http://dx.doi.org/10.1126/science.aag1381 (2017).
Jaiswal, S. et al. N. Engl. J. Med. 371, 2488–2498 (2014).
Yang, H. et al. Oncogene 32, 663–669 (2013).
Li, Z. et al. Blood 118, 4509–4518 (2011).
Busque, L. et al. Nature Genet. 44, 1179–1181 (2012).
Zhang, Q. et al. Nature 525, 389–393 (2015).
Coller, B. S. Arterioscler. Thromb. Vasc. Biol. 25, 658–670 (2005).
Dutta, P. et al. Nature 487, 325–329 (2012).
Yvan-Charvet, L. et al. Science 328, 1689–1693 (2010).
Murphy, A. J. et al. J. Clin. Invest. 121, 4138–4149 (2011).
Wang, W. et al. Circ. Res. 119, e91–e103 (2016).
Kleppe, M. et al. Cancer Discov. 5, 316–331 (2015).
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Tall, A., Levine, R. Commonality with cancer. Nature 543, 45–47 (2017). https://doi.org/10.1038/nature21505
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DOI: https://doi.org/10.1038/nature21505
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