Extended Data Figure 9 : Selective constraints and enrichment of GWAS trait and eQTL-associated SNPs at lncRNA loci.

From: An atlas of human long non-coding RNAs with accurate 5′ ends

Extended Data Figure 9

a, Selective constraints between species (phastCons38) and within human population (derived allele frequency39). b, Enrichment of GWAS SNPs. Only lead GWAS SNPs15 were used (Methods). c, Enrichment of PICS17 fine-mapped SNPs in global (all versus all) or focused (immune versus immune) analysis (Methods). d, Enrichment of GTEx eQTL SNPs16 associated with expression of mRNAs. Circles represent means and the error bars represent their 99.99% confidence intervals.