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Biological techniques

Stomach growth in a dish

A protocol has been developed to grow structures that resemble the main part of the stomach in vitro from human embryonic stem cells — an advance that provides insights into stomach development. See Article p.182

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Figure 1: Growth of a gastric corpus.

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References

  1. Willet, S. G. & Mills, J. C. Cell. Mol. Gastroenterol. Hepatol. 2, 546–559 (2016).

    Article  Google Scholar 

  2. McCracken, K. W. et al. Nature 541, 182–187 (2017).

    Article  ADS  CAS  Google Scholar 

  3. Schweiger, P. J. & Jensen, K. B. Curr. Opin. Cell Biol. 43, 22–29 (2016).

    Article  CAS  Google Scholar 

  4. Sato, T. & Clevers, H. Methods Mol. Biol. 945, 319–328 (2013).

    Article  Google Scholar 

  5. McCracken, K. W. et al. Nature 516, 400–404 (2014).

    Article  ADS  CAS  Google Scholar 

  6. Schlaermann, P. et al. Gut 65, 202–213 (2016).

    Article  CAS  Google Scholar 

  7. Bartfeld, S. et al. Gastroenterology 148, 126–136 (2015).

    Article  Google Scholar 

  8. Noguchi, T.-A. K. et al. Nature Cell Biol. 17, 984–993 (2015).

    Article  CAS  Google Scholar 

  9. Watson, C. L. et al. Nature Med. 20, 1310–1314 (2014).

    Article  CAS  Google Scholar 

  10. Mills, J. C. & Sansom, O. J. Sci. Signal. 8, re8 (2015).

    Article  Google Scholar 

  11. El-Zimaity, H. M. T., Ota, H., Graham, D. Y., Akamatsu, T. & Katsuyama, T. Cancer 94, 1428–1436 (2002).

    Article  Google Scholar 

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Correspondence to Jason C. Mills.

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Sáenz, J., Mills, J. Stomach growth in a dish. Nature 541, 160–161 (2017). https://doi.org/10.1038/nature21110

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