Extended Data Figure 9 : Surface electrostatic potential.

From: Structure of a CLC chloride ion channel by cryo-electron microscopy

Extended Data Figure 9

Surface electrostatics of the CLC-K channel (class 1) compared with the EcCLC and CmCLC transporters. Left panels show side views with one subunit in a surface representation and the other in a ribbon representation. Electrostatic potential is indicated by the colour scale (bottom left). Views from the extracellular side (blue arrow) and intracellular side (red arrow) are shown in the middle and right panels, respectively. The entrances to the Cl ion pathway are indicated by dashed circles. Mobile monovalent cation and anion species at 0.15 M each were included in the electrostatic potential calculations.