Extended Data Figure 2 : Conformations of CTD peptides bound to bat FluA polymerase compared to other Pol-II-interacting factors.

From: Structural basis of an essential interaction between influenza polymerase and Pol II CTD

Extended Data Figure 2

Structures of proteins bound to SeP5 or SeP2-SeP5 CTD peptides are shown in grey cartoon, the peptides (stick representation) are coloured to highlight their position and zoomed in next to their corresponding structure. a, b, Binding site 1 (a) and site 2 (b) of bat FluA polymerase, with the corresponding parts of the CTD SeP5 peptides. c, SeP2–SeP5 CTD bound to the peptidyl-prolyl isomerase Pin1 (PDB: 1F8A). d, SeP5 CTD bound to Candida albicans capping-enzyme Cgt1 (PDB: 1P16). e, SeP2–SeP5 CTD bound to mammalian capping-enzyme Mce1 (PDB: 3RTX). f, SeP2–SeP5 CTD bound to Schizosaccharomyces pombe capping-enzyme Pce1 (PDB: 4PZ6). g, SeP5 CTD bound to human serine phosphatase Ssu72 (PDB: 3O2Q).